Assembly of protein-directed fluorescent gold nanoclusters for high-sensitivity detection of uranyl ions.
Int J Biol Macromol
; 278(Pt 3): 134883, 2024 Oct.
Article
in En
| MEDLINE
| ID: mdl-39168203
ABSTRACT
Uranium is a key element in the nuclear industry, whose accidental release causes health and environmental problems. In this paper, a protein-directed fluorescent sensor with aggregation-induced emission characteristics (gold nanoclusters@ovalbumin, AuNCs@OVA) was synthesized for the detection of UO22+ with high sensitivity and selectivity. The sensor exhibited good fluorescence stability, and its fluorescence intensity could be selectively enhanced by UO22+. Based on FT-IR and XPS analyses, the increase in fluorescence intensity of AuNCs@OVA after the addition of UO22+ was attributed to aggregation induced by the complexation between UO22+ and the amino, carboxyl, hydroxyl, and phosphate groups of ovalbumin. The detection limit was determined to be 34.4 nM, and the sensor showed excellent ion selectivity for UO22+. In combination with a smartphone program, the sensor could realize the real-time detection of UO22+ in a quantitative and portable way.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Uranium
/
Metal Nanoparticles
/
Gold
Language:
En
Journal:
Int J Biol Macromol
Year:
2024
Document type:
Article
Country of publication:
Netherlands