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Flow diversion of cerebral aneurysms in Type I osteogenesis imperfecta: A case report of the first two treatments in humans.
Zarrin, David A; Campos, Jessica K; Meyer, Benjamen M; Himstead, Alexander S; Laghari, Fahad; Collard de Beaufort, Jonathan C; Golshani, Kiarash; Beaty, Narlin B; Bender, Matthew T; Colby, Geoffrey P; Coon, Alexander L.
Affiliation
  • Zarrin DA; David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
  • Campos JK; Department of Neurological Surgery, University of California Irvine, Orange, CA, USA.
  • Meyer BM; College of Medicine, University of Arizona, Tucson, AZ, USA.
  • Himstead AS; Department of Neurological Surgery, University of California Irvine, Orange, CA, USA.
  • Laghari F; Carondelet Neurological Institute, St. Joseph's Hospital, Tucson, AZ, USA.
  • Collard de Beaufort JC; State University of New York Upstate Medical University, Syracuse, NY, USA.
  • Golshani K; Department of Neurological Surgery, University of California Irvine, Orange, CA, USA.
  • Beaty NB; Florida State University, Tallahassee Memorial Hospital, Tallahassee, FL, USA.
  • Bender MT; Department of Neurosurgery, University of Rochester, Rochester, NY, USA.
  • Colby GP; Department of Neurosurgery, University of California Los Angeles, Los Angeles, CA, USA.
  • Coon AL; Carondelet Neurological Institute, St. Joseph's Hospital, Tucson, AZ, USA.
SAGE Open Med Case Rep ; 12: 2050313X241274243, 2024.
Article in En | MEDLINE | ID: mdl-39185069
ABSTRACT
Osteogenesis imperfecta (OI) predisposes individuals to easy bone fracture, vessel fragility, and platelet dysfunction. We report the first known case of neurointerventional treatment with flow diversion of intracranial aneurysms in a patient with OI. A 62 year-old female with known OI Type I, history of >40 lifetime bone fractures and hypertension, underwent workup for transient ischemic attacks revealing a 4-mm right A1 segment aneurysm in 2016. Perioperative dual antiplatelet therapy was aspirin 81 mg and clopidogrel 37.5 mg daily. Tri-axial access was utilized to deploy a 3.5 × 16-mm Pipeline Flex device without complication. Two-month follow-up revealed Raymond I (O'Kelly Marotta I) obliteration of the aneurysm. Five-year follow-up revealed a de novo left-sided 3-mm A1-A2 junction aneurysm. A 4 × 12-mm Surpass Evolve was placed without complication. Six-month follow-up revealed Raymond I (O'Kelly Marotta I) obliteration of the second aneurysm. The patient remained asymptomatic at all follow-up visits.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: SAGE Open Med Case Rep Year: 2024 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: SAGE Open Med Case Rep Year: 2024 Document type: Article Affiliation country: United States Country of publication: United kingdom