Your browser doesn't support javascript.
loading
Prolonged detection of BPV2 in urine and blood of papillomatosis-affected cattle not grazing bracken fern.
Tibúrcio-Júnior, Elias; Carrazzoni, Patricia G; Tenorio-Filho, Fernando; Pontes, Nayara E; Alves, Ryan V; de Freitas, Antonio Carlos; Silva, Maria Angélica Ramos.
Affiliation
  • Tibúrcio-Júnior E; Federal University of Pernambuco - UFPE, Av. Professor Moraes Rego, 1235 -Cidade Universitária, Recife, 50670-901, Brazil.
  • Carrazzoni PG; Agronomic Institute of Pernambuco - IPA, Av. General San Martin, 1371 Bongi, Recife, 50761-000, Brazil.
  • Tenorio-Filho F; Agronomic Institute of Pernambuco - IPA, Av. General San Martin, 1371 Bongi, Recife, 50761-000, Brazil.
  • Pontes NE; Federal University of Pernambuco - UFPE, Av. Professor Moraes Rego, 1235 -Cidade Universitária, Recife, 50670-901, Brazil.
  • Alves RV; Federal Institute of Education, Science, and Technology of Paraíba - IFPB, Av Santa Rita de Cássia, 1900, Cabedelo, 58.015-430, Brazil.
  • de Freitas AC; Federal University of Pernambuco - UFPE, Av. Professor Moraes Rego, 1235 -Cidade Universitária, Recife, 50670-901, Brazil. acf_ufpe@yahoo.com.br.
  • Silva MAR; Federal University of Pernambuco - UFPE, Av. Professor Moraes Rego, 1235 -Cidade Universitária, Recife, 50670-901, Brazil.
Vet Res Commun ; 2024 Aug 26.
Article in En | MEDLINE | ID: mdl-39186129
ABSTRACT
BPV-2 infection can cause bladder infections in cattle that, when associated with bracken fern consumption, can progress to cancerous bladder tumors and also present as bovine enzootic hematuria (BEH). This study aimed to evaluate the prolonged natural BPV-2 infection in the blood and urine of cattle, excluding bracken fern consumption. Thirteen Girolando papillomatosis-affected cattle with no bracken fern contact history were monitored for 20 months. Blood, urine, and wart samples were collected for BPV-2 detection and clinical laboratory analyses. All animals showed the presence of BPV-2 in papillomas and blood, and 92.85% showed BPV-2 in urine, suggesting viral dissemination in the urinary tract. Despite all animals being infected with BPV-2, none showed BEH signs during the study. Thus, it was observed that BPV-2 infection alone didn't induce BEH over 20 months, implying a complex interaction with environmental factors or genetic predisposition. This underlines bracken fern consumption's critical role in urinary bladder carcinogenesis. The study underscores BEH's pathogenesis complexity, advocating longitudinal studies to comprehend BPV-2's role fully.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Vet Res Commun Year: 2024 Document type: Article Affiliation country: Brazil Country of publication: Switzerland

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Vet Res Commun Year: 2024 Document type: Article Affiliation country: Brazil Country of publication: Switzerland