Canine Distemper Virus: Origins, Mutations, Diagnosis, and Epidemiology in Mexico.
Life (Basel)
; 14(8)2024 Aug 13.
Article
in En
| MEDLINE
| ID: mdl-39202744
ABSTRACT
This review provides an overview of the canine distemper virus (CDV), a highly infectious pathogen causing severe disease in domestic dogs and wildlife. It shares genetic similarities with the human measles virus (HMV) in humans and the rinderpest virus (RPV) in cattle. The origin of CDV likely involves a mutation from human measles strains, possibly in the New World, with subsequent transmission to dogs. CDV has been globally observed, with an increasing incidence in various animal populations. Genomic mutations, especially in the H protein, contribute to its ability to infect different hosts. Diagnosis by molecular techniques like RT-qPCR offers rapid and sensitive detection when compared with serological tests. Genomic sequencing is vital for understanding CDV evolution and designing effective control strategies. Overall, CDV poses a significant threat, and genomic sequencing enhances our ability to manage and prevent its spread. Here, the epidemiology of CDV principally in Mexico is reviewed.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Country/Region as subject:
Mexico
Language:
En
Journal:
Life (Basel)
Year:
2024
Document type:
Article
Affiliation country:
Mexico
Country of publication:
Switzerland