Why is single sample rule out of non-ST elevation myocardial infarction using high-sensitivity cardiac troponin T safe when analytical imprecision is so high? A joint statistical and clinical demonstration.

Hatherley, James Daniel; Miller, Guy; Collinson, Paul; Shantsila, Eduard; Fearon, Hannah; Lambert, Angela; Khand, Yusuf; Khand, Aleem

Hatherley, James Daniel; Miller, Guy; Collinson, Paul; Shantsila, Eduard; Fearon, Hannah; Lambert, Angela; Khand, Yusuf; Khand, Aleem.

Affiliation

Hatherley JD; 4595 Liverpool University Hospitals NHS Foundation Trust , Cardiology Department, Liverpool, UK.
Miller G; University of Liverpool, Faculty of Health and Life Sciences, Liverpool, UK.
Collinson P; 4595 Liverpool University Hospitals NHS Foundation Trust , Cardiology Department, Liverpool, UK.
Shantsila E; St George's University of London, Clinical Blood Sciences, London, UK.
Fearon H; University of Liverpool, Faculty of Health and Life Sciences, Liverpool, UK.
Lambert A; Liverpool Clinical Laboratories, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Khand Y; Liverpool Clinical Laboratories, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Khand A; Trinity College Cambridge, University of Cambridge, Cambridge, UK.

Clin Chem Lab Med ; 2024 Sep 02.

Article in En | MEDLINE | ID: mdl-39217629

Key words

acute coronary syndrome; cardiac markers; immunoassay; statistics; troponin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Clin Chem Lab Med Journal subject: QUIMICA CLINICA / TECNICAS E PROCEDIMENTOS DE LABORATORIO Year: 2024 Document type: Article Country of publication: Germany

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