Patient-specific guides for consistently achieving R0 bone margins after resection of primary malignant bone tumors of the pelvis.
World J Surg Oncol
; 22(1): 233, 2024 Sep 04.
Article
in En
| MEDLINE
| ID: mdl-39232698
ABSTRACT
AIMS:
Primary malignant bone tumor of the pelvis is an uncommon lesion, the resection of which via freehand osteotomy is subject to inaccuracy due to its three-dimensional anatomy. Patient-Specific Guides (PSG), also called Patient-Specific Instruments (PSI) are essential to ensure surgical planning and resection adequacy. Our aim was to assess their use and effectiveness.METHODS:
A monocentric retrospective study was conducted on 42 adult patients who underwent PSG-based resection of a primary malignant bone tumor of the pelvis. The primary outcome was the proportion of R0 bone margins. The secondary outcomes were the proportion of overall R0 margins, considering soft-tissue resection, the cumulative incidence of local recurrence, and the time of production for the guides. A comparison to a previous series at our institution was performed regarding histological margins.RESULTS:
Using PSGs, 100% R0 safe bone margin was achieved, and 88% overall R0 margin due to soft-tissue resection being contaminated, while the comparison to the previous series showed only 80% of R0 safe bone margin. The cumulative incidences of local recurrence were 10% (95% CI 4-20%) at one year, 15% (95% CI 6-27%) at two years, and 19% (95% CI 8-33%) at five years. The median overall duration of the fabrication process of the guide was 35 days (Q1-Q3 26-47) from the first contact to the surgery date.CONCLUSIONS:
Patient-Specific Guides can provide a reproducible safe bony margin.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Bone Neoplasms
/
Margins of Excision
/
Neoplasm Recurrence, Local
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
World J Surg Oncol
Year:
2024
Document type:
Article
Affiliation country:
France
Country of publication:
United kingdom