Stopping runaway seizures with a chill pill.

Buchanan, Gordon F

Buchanan, Gordon F.

Affiliation

Buchanan GF; University of Iowa, Carver College of Medicine, Iowa City, United States.

Elife ; 132024 Sep 05.

Article in En | MEDLINE | ID: mdl-39235854

ABSTRACT

ABSTRACT

The neuropeptide neurotensin can reduce status epilepticus and its associated consequences through induction of therapeutic hypothermia when bound to a molecule that can penetrate the blood-brain barrier.

Subject(s)

Seizures; Humans; Seizures/drug therapy; Neurotensin/metabolism; Blood-Brain Barrier/metabolism; Status Epilepticus/drug therapy; Animals; Hypothermia, Induced

Key words

epilepsy; hypothermia; mouse; neuroscience; neurotensin; seizures; status epilepticus

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Seizures Limits: Animals / Humans Language: En Journal: Elife Year: 2024 Document type: Article Affiliation country: United States Country of publication: United kingdom

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