Inhibition of cytochrome P-450 activity in rat liver microsomes by the naturally occurring flavonoid, quercetin.

Sousa, R L; Marletta, M A

Sousa, R L; Marletta, M A.

Arch Biochem Biophys ; 240(1): 345-57, 1985 Jul.

Article in En | MEDLINE | ID: mdl-3925883

Subject(s)

Cytochrome P-450 Enzyme Inhibitors; Flavonoids/pharmacology; Microsomes, Liver/enzymology; Quercetin/pharmacology; Animals; Benzo(a)pyrene/metabolism; Binding Sites; Cytochrome P-450 CYP1A1; Hydroxylation; In Vitro Techniques; Male; NADPH-Ferrihemoprotein Reductase/antagonists & inhibitors; Nitroanisole O-Demethylase/antagonists & inhibitors; Oxidoreductases/antagonists & inhibitors; Rats; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Quercetin / Flavonoids / Microsomes, Liver / Cytochrome P-450 Enzyme Inhibitors Limits: Animals Language: En Journal: Arch Biochem Biophys Year: 1985 Document type: Article Country of publication: United States

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