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Machine learning-based classification of Parkinson's disease using acoustic features: Insights from multilingual speech tasks.
Jeong, Seung-Min; Song, Young-Do; Seok, Chae-Lin; Lee, Jun-Young; Lee, Eui Chul; Kim, Han-Joon.
Affiliation
  • Jeong SM; Department of AI & Informatics, Graduate School, Sangmyung University, Hongjimun 2-Gil 20, Jongno-gu, Seoul, 03016, Republic of Korea.
  • Song YD; Department of AI & Informatics, Graduate School, Sangmyung University, Hongjimun 2-Gil 20, Jongno-gu, Seoul, 03016, Republic of Korea.
  • Seok CL; Department of AI & Informatics, Graduate School, Sangmyung University, Hongjimun 2-Gil 20, Jongno-gu, Seoul, 03016, Republic of Korea.
  • Lee JY; Department of Psychiatry, Seoul National University College of Medicine & SMG-SNU Boramae Medical Center, 20, Boramae-Ro 5-gil, Dongjak-gu, Seoul, 07061, Republic of Korea.
  • Lee EC; Department of Human-Centered Artificial Intelligence, Sangmyung University, Hongjimun 2-Gil 20, Jongno-gu, Seoul, 03016, Republic of Korea. Electronic address: eclee@smu.ac.kr.
  • Kim HJ; Department of Neurology, Seoul National University College of Medicine, Seoul National University Hospital, Daehak-ro 101, Jongno-gu, Seoul, 03080, Republic of Korea.
Comput Biol Med ; 182: 109078, 2024 Sep 11.
Article in En | MEDLINE | ID: mdl-39265476
ABSTRACT
This study advances the automation of Parkinson's disease (PD) diagnosis by analyzing speech characteristics, leveraging a comprehensive approach that integrates a voting-based machine learning model. Given the growing prevalence of PD, especially among the elderly population, continuous and efficient diagnosis is of paramount importance. Conventional monitoring methods suffer from limitations related to time, cost, and accessibility, underscoring the need for the development of automated diagnostic tools. In this paper, we present a robust model for classifying speech patterns in Korean PD patients, addressing a significant research gap. Our model employs straightforward preprocessing techniques and a voting-based machine learning approach, demonstrating superior performance, particularly when training data is limited. Furthermore, we emphasize the effectiveness of the eGeMAPSv2 feature set in PD analysis and introduce new features that substantially enhance classification accuracy. The proposed model, achieving an accuracy of 84.73 % and an area under the ROC (AUC) score of 92.18 % on a dataset comprising 100 Korean PD patients and 100 healthy controls, offers a practical solution for automated diagnosis applications, such as smartphone apps. Future research endeavors will concentrate on enhancing the model's performance and delving deeper into the relationship between high-importance features and PD.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Comput Biol Med / Comput. biol. med / Computers in biology and medicine Year: 2024 Document type: Article Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Comput Biol Med / Comput. biol. med / Computers in biology and medicine Year: 2024 Document type: Article Country of publication: United States