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Dynamics of Splenic Transient Elastography in Patients With Alcohol Use Disorder.
Khalid, Mian B; Blaney, Hanna L; Vittal, Anusha; Yang, Alexander H; Asif, Bilal A; Kamal, Natasha; Wright, Elizabeth C; Koh, Chris; George, David; Goldman, David; Horneffer, Yvonne; Diazgranados, Nancy; Heller, Theo.
Affiliation
  • Khalid MB; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Blaney HL; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Vittal A; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Yang AH; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Asif BA; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Kamal N; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Wright EC; Office of the Director, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Koh C; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • George D; Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA .
  • Goldman D; Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA .
  • Horneffer Y; Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA .
  • Diazgranados N; Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA .
  • Heller T; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Clin Transl Gastroenterol ; 2024 Sep 23.
Article in En | MEDLINE | ID: mdl-39311428
ABSTRACT

INTRODUCTION:

Splenic stiffness (SS) measurement (SSM) is an evolving noninvasive assessment to evaluate portal hypertension. Studies with respect to SSM in patients with alcohol use disorder are limited.

METHODS:

We studied patients seeking treatment for alcohol use disorder in an inpatient treatment protocol at the National Institutes of Health and parsed SSM into 3 groups based on degree of change.

RESULTS:

The improved SS group had statistically higher initial SSM and a nonstatistically increased liver stiffness measurement compared with others.

DISCUSSION:

SS is dynamic in a subset of patients immediately after alcohol cessation, and improved SS is associated with a normalization of platelet count.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Clin Transl Gastroenterol Year: 2024 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Clin Transl Gastroenterol Year: 2024 Document type: Article Affiliation country: United States Country of publication: United States