Predictors of Morbidity, Mortality, and Hospital Utilization Among Endoscopic Retrograde Cholangiopancreatography-related Hospitalizations: A Five-year Nationwide Assessment.
J Clin Gastroenterol
; 2024 Sep 23.
Article
in En
| MEDLINE
| ID: mdl-39312508
ABSTRACT
OBJECTIVE:
We aimed to assess the hospital frailty risk score on the inpatient mortality, morbidity, and health care resource utilization among endoscopic retrograde cholangiopancreatography (ERCP)-related hospitalizations.BACKGROUND:
Data regarding the inpatient mortality, morbidity, and health care resource utilization of ERCP among frail individuals remain limited. MATERIALS ANDMETHODS:
Using the Nationwide Inpatient Sample, we compared the odds of inpatient mortality and morbidity of ERCP-related hospitalizations among individuals with low frailty scores, intermediate frailty scores (IFSs), and high frailty scores (HFSs).RESULTS:
Overall, 776,025 ERCP-related hospitalizations were recorded from 2016 to 2020. 552,045 had a low frailty score, whereas 217,875 had an IFS, and 6105 had an HFS. Frail individuals had a 5-fold increase in mortality [IFS adjusted odds ratio (aOR) = 4.81, 95% CI 3.77-6.14; HFS aOR = 4.62, 95% CI 2.48-8.63]. An IFS was associated with a 24% increase in post-ERCP pancreatitis (aOR = 1.25, 95% CI 1.11-1.41), a 3-fold increase in post-ERCP bleeding (aOR = 2.59, 95% CI 1.82-3.67), and a 2-fold increase in post-ERCP duct perforation (aOR = 1.91, 95% CI 1.38-2.64). Frail individuals experienced higher odds of in-hospital morbidity, including secondary sepsis, respiratory failure, acute kidney injury, cerebrovascular accidents, deep vein thrombosis, and pulmonary embolism.CONCLUSIONS:
In summary, our study presents strong evidence in support of using the hospital frailty risk score as an index to predict mortality and morbidity during ERCP-related hospitalizations. Additional caution is warranted in the management of frail individuals undergoing ERCP.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
J Clin Gastroenterol
Year:
2024
Document type:
Article
Country of publication:
United States