The TolC and Lipopolysaccharide-Specific Escherichia coli Bacteriophage TLS-the Tlsvirus Archetype Virus.
Phage (New Rochelle)
; 5(3): 173-183, 2024 Sep.
Article
in En
| MEDLINE
| ID: mdl-39372356
ABSTRACT
Introduction:
TLS is a virulent bacteriophage of Escherichia coli that utilizes TolC and lipopolysaccharide as its cell surface receptors.Methods:
The genome was reannotated using the latest online resources and compared to other T1-like phages.Results:
The TLS genome consists of 49,902 base pairs, encoding 86 coding sequences that display considerable sequence similarity with the T1 phage genome. It also contains 18 intergenic 21-base long repeats, each of them upstream of a predicted start codon and in the direction of transcription. Data revealed that DNA packaging occurs through the pac site-mediated headful mechanism.Conclusions:
Based on sequence analysis of its genome, TLS belongs to the Drexlerviridae family and represents the type member of the Tlsvirus genus.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Phage (New Rochelle)
Year:
2024
Document type:
Article
Affiliation country:
Canada
Country of publication:
United States