Altered thymidine-thymidylate kinases from strains of herpes simplex virus with modified drug sensitivities to acyclovir and (E)-5-(2-bromovinyl)-2'-deoxyuridine.

Fyfe, J A; McKee, S A; Keller, P M

Fyfe, J A; McKee, S A; Keller, P M.

Mol Pharmacol ; 24(2): 316-23, 1983 Sep.

Article in En | MEDLINE | ID: mdl-6310366

Subject(s)

Acyclovir/pharmacology; Antiviral Agents/pharmacology; Bromodeoxyuridine/analogs & derivatives; Nucleoside-Phosphate Kinase/isolation & purification; Phosphotransferases/isolation & purification; Simplexvirus/enzymology; Thymidine Kinase/isolation & purification; Bromodeoxyuridine/pharmacology; Drug Resistance, Microbial; Genetic Code; Phosphorylation; Simplexvirus/drug effects; Substrate Specificity

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Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Phosphotransferases / Thymidine Kinase / Bromodeoxyuridine / Acyclovir / Simplexvirus / Nucleoside-Phosphate Kinase Type of study: Diagnostic_studies Language: En Journal: Mol Pharmacol Year: 1983 Document type: Article Country of publication: United States

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