In vivo O-de-ethylation of phenacetin in 3-methylcholanthrene-pretreated rats: gut wall and liver first-pass metabolism. | J Pharmacol Exp Ther;225(1): 153-7, 1983 Apr. | MEDLINE

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In vivo O-de-ethylation of phenacetin in 3-methylcholanthrene-pretreated rats: gut wall and liver first-pass metabolism.

Klippert, P J; Littel, R J; Noordhoek, J.

J Pharmacol Exp Ther ; 225(1): 153-7, 1983 Apr.

Article in En | MEDLINE | ID: mdl-6834267

Subject(s)

Intestinal Mucosa/metabolism; Liver/metabolism; Methylcholanthrene/administration & dosage; Phenacetin/blood; Acetaminophen/blood; Animals; Biological Availability; Intestinal Absorption/drug effects; Kinetics; Male; Rats; Rats, Inbred Strains

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Collection: 01-internacional Database: MEDLINE Main subject: Phenacetin / Intestinal Mucosa / Liver / Methylcholanthrene Limits: Animals Language: En Journal: J Pharmacol Exp Ther Year: 1983 Document type: Article Country of publication: United States

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Collection: 01-internacional Database: MEDLINE Main subject: Phenacetin / Intestinal Mucosa / Liver / Methylcholanthrene Limits: Animals Language: En Journal: J Pharmacol Exp Ther Year: 1983 Document type: Article Country of publication: United States