Experimental data on the prevention of retrolental fibroplasia by D-penicillamine.
Acta Paediatr Acad Sci Hung
; 21(2-3): 131-8, 1980.
Article
in En
| MEDLINE
| ID: mdl-6894055
ABSTRACT
Superoxide dismutase activity of alveolar macrophages, lung, liver, retina and choroid has been studied in rats and rabbits exposed to oxygen at high concentration by itself and in combination with D-penicillamine. Prolonged hyperoxia caused an increase in superoxide dismutase activity while D-penicillamine was found to inhibit the inductive effect of oxygen. It is assumed that the antioxidative effect of D-penicillamine makes it unnecessary to augment the production of superoxide dismutase.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Penicillamine
/
Retinopathy of Prematurity
Type of study:
Etiology_studies
Limits:
Animals
/
Humans
/
Newborn
Language:
En
Journal:
Acta Paediatr Acad Sci Hung
Year:
1980
Document type:
Article