Interactions between ethanol metabolism and mixed-function oxidation in perfused rat liver: inhibition of p-nitroanisole O-demethylation.

Reinke, L A; Kauffman, F C; Belinsky, S A; Thurman, R G

Reinke, L A; Kauffman, F C; Belinsky, S A; Thurman, R G.

J Pharmacol Exp Ther ; 213(1): 70-8, 1980 Apr.

Article in En | MEDLINE | ID: mdl-6987376

Subject(s)

Ethanol/metabolism; Liver/enzymology; Mixed Function Oxygenases/antagonists & inhibitors; NADP/metabolism; Nitroanisole O-Demethylase/antagonists & inhibitors; Oxidoreductases/antagonists & inhibitors; Acetaldehyde/pharmacology; Alcohol Oxidoreductases/antagonists & inhibitors; Animals; Anisoles/pharmacology; Aspartic Acid/pharmacology; Ethanol/pharmacology; Female; Fomepizole; In Vitro Techniques; Microsomes, Liver/enzymology; Perfusion; Pyrazoles/pharmacology; Rats

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Collection: 01-internacional Database: MEDLINE Main subject: Oxidoreductases / Ethanol / Mixed Function Oxygenases / Liver / NADP / Nitroanisole O-Demethylase Limits: Animals Language: En Journal: J Pharmacol Exp Ther Year: 1980 Document type: Article Country of publication: United States

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