Nonhydrolyzable phosphotyrosyl mimetics for the preparation of phosphatase-resistant SH2 domain inhibitors.

Burke, T R; Smyth, M S; Otaka, A; Nomizu, M; Roller, P P; Wolf, G; Case, R; Shoelson, S E

Burke, T R; Smyth, M S; Otaka, A; Nomizu, M; Roller, P P; Wolf, G; Case, R; Shoelson, S E.

Affiliation

Burke TR; Laboratory of Medicinal Chemistry, NCI, National Institutes of Health, Bethesda, Maryland 20892.

Biochemistry ; 33(21): 6490-4, 1994 May 31.

Article in En | MEDLINE | ID: mdl-7515682

Subject(s)

Enzyme Inhibitors/chemical synthesis; Oncogene Protein pp60(v-src); Phenylalanine/metabolism; Phosphoric Monoester Hydrolases/metabolism; Tyrosine/analogs & derivatives; Amino Acid Sequence; Enzyme Inhibitors/metabolism; Enzyme Inhibitors/pharmacology; Hydrolysis; Molecular Sequence Data; Phenylalanine/analogs & derivatives; Phosphotyrosine; Tyrosine/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Phenylalanine / Tyrosine / Oncogene Protein pp60(v-src) / Phosphoric Monoester Hydrolases / Enzyme Inhibitors Language: En Journal: Biochemistry Year: 1994 Document type: Article

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