Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds.

Fesen, M R; Pommier, Y; Leteurtre, F; Hiroguchi, S; Yung, J; Kohn, K W

Fesen, M R; Pommier, Y; Leteurtre, F; Hiroguchi, S; Yung, J; Kohn, K W.

Affiliation

Fesen MR; Laboratory of Molecular Pharmacology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.

Biochem Pharmacol ; 48(3): 595-608, 1994 Aug 03.

Article in En | MEDLINE | ID: mdl-7520698

Subject(s)

Caffeic Acids/pharmacology; DNA Nucleotidyltransferases/antagonists & inhibitors; Flavonoids/pharmacology; HIV-1/enzymology; Phenylethyl Alcohol/analogs & derivatives; Base Sequence; Cations, Divalent; DNA/drug effects; DNA Nucleotidyltransferases/genetics; Dose-Response Relationship, Drug; Integrases; Kinetics; Molecular Sequence Data; Oligonucleotides/metabolism; Phenylethyl Alcohol/pharmacology; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Phenylethyl Alcohol / Flavonoids / Caffeic Acids / HIV-1 / DNA Nucleotidyltransferases Type of study: Prognostic_studies Language: En Journal: Biochem Pharmacol Year: 1994 Document type: Article

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