Growth hormone rapidly activates rat serine protease inhibitor 2.1 gene transcription and induces a DNA-binding activity distinct from those of Stat1, -3, and -4.

Thomas, M J; Gronowski, A M; Berry, S A; Bergad, P L; Rotwein, P

Thomas, M J; Gronowski, A M; Berry, S A; Bergad, P L; Rotwein, P.

Affiliation

Thomas MJ; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110.

Mol Cell Biol ; 15(1): 12-8, 1995 Jan.

Article in En | MEDLINE | ID: mdl-7528325

Subject(s)

DNA-Binding Proteins/metabolism; Gene Expression Regulation, Enzymologic/drug effects; Growth Hormone/pharmacology; Nuclear Proteins/genetics; Promoter Regions, Genetic; Serine Proteinase Inhibitors/genetics; Transcription Factors/metabolism; Animals; Base Sequence; Male; Molecular Sequence Data; Nuclear Proteins/metabolism; Oligodeoxyribonucleotides/chemistry; Phosphotyrosine; RNA, Messenger/genetics; Rats; Rats, Sprague-Dawley; STAT1 Transcription Factor; STAT3 Transcription Factor; STAT4 Transcription Factor; Signal Transduction; Trans-Activators/metabolism; Transcription, Genetic/drug effects; Tyrosine/analogs & derivatives; Tyrosine/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Growth Hormone / Nuclear Proteins / Gene Expression Regulation, Enzymologic / Serine Proteinase Inhibitors / Promoter Regions, Genetic / DNA-Binding Proteins Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Cell Biol Year: 1995 Document type: Article

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