Glucocorticoid negative feedback in pituitary corticotropes. Pivotal role for calcineurin inhibition of adenylyl cyclase.

Shipston, M J; Hernando, F; Barnard, R J; Antoni, F A

Shipston, M J; Hernando, F; Barnard, R J; Antoni, F A.

Affiliation

Shipston MJ; Department of Pharmacology, University of Edinburgh, Scotland, UK.

Ann N Y Acad Sci ; 746: 453-5, 1994 Nov 30.

Article in En | MEDLINE | ID: mdl-7529975

Subject(s)

Adenylyl Cyclase Inhibitors; Adrenocorticotropic Hormone/metabolism; Calmodulin-Binding Proteins/physiology; Corticotropin-Releasing Hormone/pharmacology; Dexamethasone/pharmacology; Phosphoprotein Phosphatases/physiology; Animals; Calcimycin/pharmacology; Calcineurin; Calcium/metabolism; Calcium/pharmacology; Cell Line; Cyclic AMP/metabolism; Cyclosporine/pharmacology; Dose-Response Relationship, Drug; Egtazic Acid/pharmacology; Feedback; Mice; Nimodipine/pharmacology; Pituitary Gland/drug effects; Pituitary Gland/physiology; Pituitary Neoplasms; Tacrolimus/pharmacology; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Calmodulin-Binding Proteins / Corticotropin-Releasing Hormone / Dexamethasone / Adrenocorticotropic Hormone / Phosphoprotein Phosphatases / Adenylyl Cyclase Inhibitors Limits: Animals Language: En Journal: Ann N Y Acad Sci Year: 1994 Document type: Article Affiliation country: United kingdom Country of publication: United States

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