Characterization of the binding of [3H]NS 257, a novel competitive AMPA receptor antagonist, to rat brain membranes and brain sections.

Nielsen, E O; Johansen, T H; Wätjen, F; Drejer, J

Nielsen, E O; Johansen, T H; Wätjen, F; Drejer, J.

Affiliation

Nielsen EO; Department of Cellular Biology, NeuroSearch A/S, Glostrup, Denmark.

J Neurochem ; 65(3): 1264-73, 1995 Sep.

Article in En | MEDLINE | ID: mdl-7543932

Subject(s)

Cerebral Cortex/metabolism; Indoles/metabolism; Receptors, AMPA/antagonists & inhibitors; Sulfonamides/metabolism; 6-Cyano-7-nitroquinoxaline-2,3-dione/metabolism; Animals; Autoradiography; Binding, Competitive; Cell Membrane/metabolism; Hydrogen-Ion Concentration; Kainic Acid/analogs & derivatives; Kainic Acid/metabolism; Male; Quinoxalines/metabolism; Rats; Rats, Wistar; Receptors, AMPA/metabolism; Thiocyanates/pharmacology; Tritium; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Cerebral Cortex / Receptors, AMPA / Indoles Limits: Animals Language: En Journal: J Neurochem Year: 1995 Document type: Article Affiliation country: Denmark Country of publication: United kingdom

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