Herbimycin A suppresses NF-kappa B activation and tyrosine phosphorylation of JAK2 and the subsequent induction of nitric oxide synthase in C6 glioma cells.

Nishiya, T; Uehara, T; Nomura, Y

Nishiya, T; Uehara, T; Nomura, Y.

Affiliation

Nishiya T; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.

FEBS Lett ; 371(3): 333-6, 1995 Sep 11.

Article in En | MEDLINE | ID: mdl-7556623

Subject(s)

Enzyme Inhibitors/pharmacology; NF-kappa B/antagonists & inhibitors; Nitric Oxide Synthase/biosynthesis; Protein-Tyrosine Kinases/metabolism; Proto-Oncogene Proteins; Quinones/pharmacology; Animals; Base Sequence; Benzoquinones; Enzyme Activation; Enzyme Induction; Glioma; Interferon-gamma/pharmacology; Janus Kinase 2; Lactams, Macrocyclic; Lipopolysaccharides/pharmacology; Molecular Sequence Data; NF-kappa B/metabolism; Oligodeoxyribonucleotides; Phosphorylation; Rats; Rifabutin/analogs & derivatives; Tumor Cells, Cultured; Tyrosine/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Quinones / Protein-Tyrosine Kinases / NF-kappa B / Proto-Oncogene Proteins / Nitric Oxide Synthase / Enzyme Inhibitors Limits: Animals Language: En Journal: FEBS Lett Year: 1995 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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