Potentiation by endothelin-1 of Ca2+ sensitivity of contractile elements depends on Ca2+ influx through L-type Ca2+ channels in the canine cerebral artery.

Tanaka, Y; Ishiro, H; Nakazawa, T; Saito, M; Ishii, K; Nakayama, K

Tanaka, Y; Ishiro, H; Nakazawa, T; Saito, M; Ishii, K; Nakayama, K.

Affiliation

Tanaka Y; Department of Pharmacology, School of Pharmaceutical Sciences, University of Shizuoka, Japan.

Gen Pharmacol ; 26(4): 855-64, 1995 Jul.

Article in En | MEDLINE | ID: mdl-7635261

Subject(s)

Calcium Channels/metabolism; Calcium/metabolism; Calcium/pharmacology; Cerebral Arteries/metabolism; Endothelins/pharmacology; Muscle, Smooth, Vascular/metabolism; Animals; Arginine/analogs & derivatives; Arginine/pharmacology; Calcium Channel Blockers/pharmacology; Calcium Channels/drug effects; Cerebral Arteries/drug effects; Dogs; Endothelins/antagonists & inhibitors; Endothelium, Vascular/drug effects; Endothelium, Vascular/physiology; Female; Fura-2; In Vitro Techniques; Indomethacin/pharmacology; Isometric Contraction/drug effects; Male; Muscle Contraction/drug effects; Muscle, Smooth, Vascular/drug effects; Nitric Oxide/antagonists & inhibitors; Nitroarginine; Type C Phospholipases/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Calcium Channels / Cerebral Arteries / Calcium / Endothelins / Muscle, Smooth, Vascular Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Gen Pharmacol Year: 1995 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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