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[Prevalence of biliary lithiasis in cirrhotics: necropsy evaluation]. / Prevalência de litíase biliar em cirróticos: avaliação necroscópica.
França, L de A; Santos, E T; Carvalho, A M; Silva, A M; Rocha, A.
Affiliation
  • França Lde A; Departamento de Patologia do Centro de Ciências Biomédicas, Universidade Federal de Uberlândia-UFU, MG.
Arq Gastroenterol ; 31(3): 92-6, 1994.
Article in Pt | MEDLINE | ID: mdl-7748105
In order to investigate a possible association between hepatic cirrhosis and biliary lithiasis, an analysis on 3,332 necropsy report diagnosis was carried out. Gallstones were present in 19.5% of 123 cirrhotics and in 4.9% of 3,209 non-cirrhotics patients. We concluded that lithiasis is significantly more frequent in cirrhotics than in non-cirrhotics. Chronic hemolysis, slow emptying of the gallbladder, and defective bile acidification by the gallbladder would explain such association. The male-to-female ratio of lithiasis occurrence was 2.08:1 in the cirrhotic group and 2.4:1 among the non-cirrhotics. This difference was not significant. Pigmentary gallstones were commoner among cirrhotics and significantly more frequent in cirrhotics than in non-cirrhotics. This would be explained by chronic hemolysis and by bilirubin conjugation defects. Lithiasis was more frequent in secondary biliary cirrhosis, followed by postnecrotic cirrhosis of viral etiology.
Subject(s)
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Collection: 01-internacional Database: MEDLINE Main subject: Cholelithiasis / Liver Cirrhosis Type of study: Prevalence_studies / Risk_factors_studies / Screening_studies Limits: Female / Humans / Male Language: Pt Journal: Arq Gastroenterol Year: 1994 Document type: Article Country of publication: Brazil
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Collection: 01-internacional Database: MEDLINE Main subject: Cholelithiasis / Liver Cirrhosis Type of study: Prevalence_studies / Risk_factors_studies / Screening_studies Limits: Female / Humans / Male Language: Pt Journal: Arq Gastroenterol Year: 1994 Document type: Article Country of publication: Brazil