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Daily events are associated with a secretory immune response to an oral antigen in men.
Stone, A A; Neale, J M; Cox, D S; Napoli, A; Valdimarsdottir, H; Kennedy-Moore, E.
Affiliation
  • Stone AA; Department of Psychiatry, State University of New York at Stony Brook 11794-8790.
Health Psychol ; 13(5): 440-6, 1994 Sep.
Article in En | MEDLINE | ID: mdl-7805639
To examine a hypothesized link between daily stressful events and secretory immunoglobulin A (sIgA) antibody, 96 adults from the community completed daily event questionnaires and gave daily saliva samples for up to 12 weeks. They also ingested a capsule of a novel protein to challenge their secretory immune systems. The questionnaire yielded measures of negative and positive experiences, of their content, and of negative and positive affect. On a within-subjects, day-to-day basis, reporting more desirable events was related to more sIgA antibody, and reporting more undesirable events was related to less. Desirable events also had lagged (1 and 2 days), positive effects on sIgA levels. Undesirable work events and desirable leisure and household events were more strongly related to sIgA than events in other categories. Positive affect related directly to sIgA, and negative mood related inversely to same-day sIgA.
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Collection: 01-internacional Database: MEDLINE Main subject: Arousal / Saliva / Stress, Psychological / Immunoglobulin A, Secretory / Antigens Type of study: Risk_factors_studies Limits: Adult / Humans / Male / Middle aged Language: En Journal: Health Psychol Year: 1994 Document type: Article Country of publication: United States
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Collection: 01-internacional Database: MEDLINE Main subject: Arousal / Saliva / Stress, Psychological / Immunoglobulin A, Secretory / Antigens Type of study: Risk_factors_studies Limits: Adult / Humans / Male / Middle aged Language: En Journal: Health Psychol Year: 1994 Document type: Article Country of publication: United States