Human (MDR1) and mouse (mdr1, mdr3) P-glycoproteins can be distinguished by their respective drug resistance profiles and sensitivity to modulators.

Tang-Wai, D F; Kajiji, S; DiCapua, F; de Graaf, D; Roninson, I B; Gros, P

Tang-Wai, D F; Kajiji, S; DiCapua, F; de Graaf, D; Roninson, I B; Gros, P.

Affiliation

Tang-Wai DF; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.

Biochemistry ; 34(1): 32-9, 1995 Jan 10.

Article in En | MEDLINE | ID: mdl-7819214

Subject(s)

ATP Binding Cassette Transporter, Subfamily B, Member 1/physiology; Drug Resistance/physiology; ATP Binding Cassette Transporter, Subfamily B, Member 1/antagonists & inhibitors; ATP Binding Cassette Transporter, Subfamily B, Member 1/biosynthesis; ATP Binding Cassette Transporter, Subfamily B, Member 1/genetics; Animals; CHO Cells; Cell Survival/drug effects; Clone Cells; Cricetinae; Cricetulus; Drug Resistance/genetics; Humans; Mice; Models, Molecular; Phenotype; Species Specificity; Transfection; Vinblastine/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Drug Resistance / ATP Binding Cassette Transporter, Subfamily B, Member 1 Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Biochemistry Year: 1995 Document type: Article Affiliation country: Canada Country of publication: United States

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