Mechanism of caffeine modulation of the antitumor activity of adriamycin.

Sadzuka, Y; Mochizuki, E; Takino, Y

Sadzuka, Y; Mochizuki, E; Takino, Y.

Affiliation

Sadzuka Y; School of Pharmaceutical Sciences, University of Shizuoka, Japan.

Toxicol Lett ; 75(1-3): 39-49, 1995 Jan.

Article in En | MEDLINE | ID: mdl-7863536

Subject(s)

Caffeine/pharmacology; Carcinoma, Ehrlich Tumor/drug therapy; DNA, Neoplasm/drug effects; Doxorubicin/pharmacology; Neoplasm Proteins/drug effects; Animals; DNA Polymerase I/drug effects; DNA Polymerase I/metabolism; DNA Polymerase II/drug effects; DNA Polymerase II/metabolism; DNA, Neoplasm/biosynthesis; Doxorubicin/metabolism; Drug Synergism; Heart/drug effects; Liver/drug effects; Liver/metabolism; Male; Mice; Mice, Inbred Strains; Myocardium/metabolism; Neoplasm Proteins/biosynthesis; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Caffeine / DNA, Neoplasm / Carcinoma, Ehrlich Tumor / Doxorubicin / Neoplasm Proteins Limits: Animals Language: En Journal: Toxicol Lett Year: 1995 Document type: Article Affiliation country: Japan Country of publication: Netherlands

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