Direct evidence of oxidative injury produced by the Alzheimer's beta-amyloid peptide (1-40) in cultured hippocampal neurons.

Harris, M E; Hensley, K; Butterfield, D A; Leedle, R A; Carney, J M

Harris, M E; Hensley, K; Butterfield, D A; Leedle, R A; Carney, J M.

Affiliation

Harris ME; Department of Pharmacology, University of Kentucky College of Medicine, Lexington 40536, USA.

Exp Neurol ; 131(2): 193-202, 1995 Feb.

Article in En | MEDLINE | ID: mdl-7895820

Subject(s)

Amyloid beta-Peptides/toxicity; Hippocampus/cytology; Neurons/drug effects; Oxidative Stress; Peptide Fragments/toxicity; Animals; Biotin/analogs & derivatives; Calcium/metabolism; Cell Death; Cells, Cultured; Electron Spin Resonance Spectroscopy; Fluoresceins; Fluorescent Dyes; Free Radicals; Glutamate-Ammonia Ligase/analysis; Microscopy, Confocal; Microscopy, Fluorescence; Nerve Tissue Proteins/analysis; Neurons/pathology; Rats; Rats, Sprague-Dawley; Spin Labels

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Amyloid beta-Peptides / Oxidative Stress / Hippocampus / Neurons Limits: Animals Language: En Journal: Exp Neurol Year: 1995 Document type: Article Affiliation country: United States Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links