Identification of the DNA-binding site for the phosphorylated VanR protein required for vancomycin resistance in Enterococcus faecium.

Holman, T R; Wu, Z; Wanner, B L; Walsh, C T

Holman, T R; Wu, Z; Wanner, B L; Walsh, C T.

Affiliation

Holman TR; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115.

Biochemistry ; 33(15): 4625-31, 1994 Apr 19.

Article in En | MEDLINE | ID: mdl-8161518

Subject(s)

Bacterial Proteins; DNA, Bacterial/metabolism; Drug Resistance, Microbial/genetics; Enterococcus faecium/genetics; Transcription Factors/chemistry; Vancomycin/pharmacology; Acetylation; Base Sequence; Binding Sites; Binding, Competitive; DNA, Bacterial/chemistry; Deoxyribonuclease I; Enterococcus faecium/drug effects; Molecular Sequence Data; Phosphorylation; Promoter Regions, Genetic; Protein Kinases/metabolism; Transcription Factors/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Proteins / Transcription Factors / DNA, Bacterial / Drug Resistance, Microbial / Vancomycin / Enterococcus faecium Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Biochemistry Year: 1994 Document type: Article

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