Transforming growth factor-beta stimulates alpha 2(I) collagen gene expression through a cis-acting element that contains an Sp1-binding site.

Inagaki, Y; Truter, S; Ramirez, F

Inagaki, Y; Truter, S; Ramirez, F.

Affiliation

Inagaki Y; Brookdale Center for Molecular Biology, Mt. Sinai School of Medicine, New York, New York 10029.

J Biol Chem ; 269(20): 14828-34, 1994 May 20.

Article in En | MEDLINE | ID: mdl-8182090

Subject(s)

Collagen/biosynthesis; Collagen/genetics; DNA/metabolism; Gene Expression/drug effects; Promoter Regions, Genetic; Sp1 Transcription Factor/metabolism; Transforming Growth Factor beta/pharmacology; Base Sequence; Binding Sites; Cells, Cultured; DNA/drug effects; DNA/genetics; Fetus; Fibroblasts/metabolism; Genes, Regulator; Humans; Molecular Sequence Data; Oligodeoxyribonucleotides/chemical synthesis; Oligodeoxyribonucleotides/metabolism; Oligodeoxyribonucleotides/pharmacology; Plasmids; Skin/metabolism; Thymidine Kinase/genetics; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: DNA / Gene Expression / Sp1 Transcription Factor / Transforming Growth Factor beta / Collagen / Promoter Regions, Genetic Limits: Humans Language: En Journal: J Biol Chem Year: 1994 Document type: Article Country of publication: United States

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