Three-dimensional quantitative structure-activity relationships of 5-HT receptor binding data for tetrahydropyridinylindole derivatives: a comparison of the Hansch and CoMFA methods.

Agarwal, A; Pearson, P P; Taylor, E W; Li, H B; Dahlgren, T; Herslöf, M; Yang, Y; Lambert, G; Nelson, D L; Regan, J W

Agarwal, A; Pearson, P P; Taylor, E W; Li, H B; Dahlgren, T; Herslöf, M; Yang, Y; Lambert, G; Nelson, D L; Regan, J W.

Affiliation

Agarwal A; Department of Medicinal Chemistry, College of Pharmacy, University of Georgia, Athens 30602.

J Med Chem ; 36(25): 4006-14, 1993 Dec 10.

Article in En | MEDLINE | ID: mdl-8258822

Subject(s)

Indoles/pharmacology; Receptors, Serotonin/drug effects; Animals; Binding Sites/drug effects; Indoles/chemistry; Indoles/metabolism; Male; Models, Molecular; Rats; Rats, Sprague-Dawley; Receptors, Serotonin/metabolism; Stereoisomerism; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Serotonin / Indoles Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 1993 Document type: Article Country of publication: United States

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