Ixr1, a yeast protein that binds to platinated DNA and confers sensitivity to cisplatin.

Brown, S J; Kellett, P J; Lippard, S J

Brown, S J; Kellett, P J; Lippard, S J.

Affiliation

Brown SJ; Department of Chemistry, Massachusetts Institute of Technology, Cambridge 02139.

Science ; 261(5121): 603-5, 1993 Jul 30.

Article in En | MEDLINE | ID: mdl-8342024

Subject(s)

Cisplatin/metabolism; Cisplatin/pharmacology; DNA Adducts; DNA, Fungal/metabolism; DNA-Binding Proteins; DNA/metabolism; Fungal Proteins/metabolism; High Mobility Group Proteins/metabolism; Saccharomyces cerevisiae Proteins; Saccharomyces cerevisiae/metabolism; Amino Acid Sequence; Cloning, Molecular; Fungal Proteins/chemistry; Fungal Proteins/genetics; Genes, Fungal; High Mobility Group Proteins/chemistry; High Mobility Group Proteins/genetics; Molecular Sequence Data; Saccharomyces cerevisiae/chemistry; Saccharomyces cerevisiae/drug effects; Saccharomyces cerevisiae/genetics

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Saccharomyces cerevisiae / DNA / DNA, Fungal / Fungal Proteins / High Mobility Group Proteins / Cisplatin / DNA Adducts / Saccharomyces cerevisiae Proteins / DNA-Binding Proteins Type of study: Diagnostic_studies Language: En Journal: Science Year: 1993 Document type: Article Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links