Acute nuclear actions of growth hormone (GH): cycloheximide inhibits inducible activator protein-1 activity, but does not block GH-regulated signal transducer and activator of transcription activation or gene expression.

Gronowski, A M; Le Stunff, C; Rotwein, P

Gronowski, A M; Le Stunff, C; Rotwein, P.

Affiliation

Gronowski AM; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

Endocrinology ; 137(1): 55-64, 1996 Jan.

Article in En | MEDLINE | ID: mdl-8536642

Subject(s)

Cell Nucleus/drug effects; Cycloheximide/pharmacology; Gene Expression/drug effects; Growth Hormone/pharmacology; Signal Transduction/drug effects; Trans-Activators/genetics; Transcription Factor AP-1/antagonists & inhibitors; Animals; Insulin-Like Growth Factor I/genetics; Liver/metabolism; Male; Nuclear Proteins/metabolism; Protein Biosynthesis; RNA, Messenger/metabolism; Rats; Rats, Sprague-Dawley; Serum Albumin/genetics; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Growth Hormone / Signal Transduction / Gene Expression / Trans-Activators / Cell Nucleus / Transcription Factor AP-1 / Cycloheximide Limits: Animals Language: En Journal: Endocrinology Year: 1996 Document type: Article Affiliation country: United States

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