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Endocrine neoplasia in New World primates.
Dias, J L; Montali, R J; Strandberg, J D; Johnson, L K; Wolff, M J.
Affiliation
  • Dias JL; Department of Pathology, Faculty of Veterinary Medicine, University of São Paulo, Brazil.
J Med Primatol ; 25(1): 34-41, 1996 Jan.
Article in En | MEDLINE | ID: mdl-8740950
Of 1,106 New World primates necropsied from the National Zoological Park (Washington, D.C.) and the Department of Comparative Pathology, Johns Hopkins University School of Medicine (Baltimore, Maryland) 22 (1.9%) animals were identified with 27 neoplasms. Of this group, nine animals (two females, seven males) had a total of 13 endocrine neoplasms. All animals were adults, with an age range of 2.7-25 years (average, 12.1 years). Seven were Callitrichidae and two were Cebidae. The adrenal gland was the most affected organ, with seven (53.8%) neoplasms, followed by the pituitary and thyroid gland with two (15.4%) cases each, and the pancreas and parathyroid gland with one tumor (7.7%) each. All neoplastic disorders were benign. Immunocytochemistry assays for growth hormone, adrenocorticotropic hormone, prolactin, follicle-stimulating hormone, luteinizing hormone, thyroid-stimulating hormone, and chromogranin A were performed on two pituitary neoplasms. Pheochromocytoma was the most frequent neoplasm, representing 5 (38.4%) of the 13 neoplasms. The remaining were thyroid cystadenoma (two, 15.4%), corticotrophic cell pituitary adenoma (two, 15.4%), adrenal ganglioneuroma (one, 7.7%), adrenal cortical adenoma (one, 7.7%), parathyroid chief-cell adenoma (one, 7.7%), and pancreatic islet-cell adenoma (one, 7.7%).
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Collection: 01-internacional Database: MEDLINE Main subject: Endocrine Gland Neoplasms / Primate Diseases Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Med Primatol Year: 1996 Document type: Article Affiliation country: Brazil Country of publication: Denmark
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Collection: 01-internacional Database: MEDLINE Main subject: Endocrine Gland Neoplasms / Primate Diseases Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Med Primatol Year: 1996 Document type: Article Affiliation country: Brazil Country of publication: Denmark