Relationship between structural properties and affinity for herpes simplex virus type 1 thymidine kinase of bromine substituted 5-heteroaromatic 2'-deoxyuridines.

Creuven, I; Evrard, C; Olivier, A; Evrard, G; Van Aerschot, A; Wigerinck, P; Herdewijn, P; Durant, F

Creuven, I; Evrard, C; Olivier, A; Evrard, G; Van Aerschot, A; Wigerinck, P; Herdewijn, P; Durant, F.

Affiliation

Creuven I; Laboratoire de Chimie Moléculaire Structurale, Facultés Universitaires Notre-Dame de la Paix, Namur, Belgium.

Antiviral Res ; 30(2-3): 63-74, 1996 May.

Article in En | MEDLINE | ID: mdl-8783799

Subject(s)

Antiviral Agents/chemistry; Antiviral Agents/metabolism; Bromine; Deoxyuridine/chemistry; Deoxyuridine/metabolism; Herpesvirus 1, Human/enzymology; Thymidine Kinase/metabolism; Deoxyuridine/analogs & derivatives; Humans; Structure-Activity Relationship; Thiophenes/chemistry; Thiophenes/metabolism; X-Ray Diffraction

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Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Thymidine Kinase / Bromine / Herpesvirus 1, Human / Deoxyuridine Type of study: Prognostic_studies Limits: Humans Language: En Journal: Antiviral Res Year: 1996 Document type: Article Affiliation country: Belgium Country of publication: Netherlands

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