Use of a semi-nested PCR diagnosis test to evaluate antifolate resistance of Plasmodium falciparum isolates.

Eldin de Pecoulas, P; Abdallah, B; Dje, M K; Basco, L K; le Bras, J; Mazabraud, A

Eldin de Pecoulas, P; Abdallah, B; Dje, M K; Basco, L K; le Bras, J; Mazabraud, A.

Affiliation

Eldin de Pecoulas P; Centre National de Référence pour la Chimiosensibilité du Paludisme, Hôpital Bichat-Claude Bernard, Paris, France.

Mol Cell Probes ; 9(6): 391-7, 1995 Dec.

Article in En | MEDLINE | ID: mdl-8808309

Subject(s)

Antimalarials/pharmacology; Folic Acid Antagonists/pharmacology; Plasmodium falciparum/drug effects; Polymerase Chain Reaction/methods; Proguanil/pharmacology; Protozoan Proteins/genetics; Pyrimethamine/pharmacology; Tetrahydrofolate Dehydrogenase/genetics; Animals; Base Sequence; Codon/genetics; DNA Mutational Analysis; DNA, Protozoan/genetics; Drug Resistance/genetics; Molecular Sequence Data; Plasmodium falciparum/enzymology; Plasmodium falciparum/genetics; Point Mutation; Protozoan Proteins/antagonists & inhibitors; Sensitivity and Specificity

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Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium falciparum / Pyrimethamine / Tetrahydrofolate Dehydrogenase / Protozoan Proteins / Proguanil / Polymerase Chain Reaction / Folic Acid Antagonists / Antimalarials Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Mol Cell Probes Journal subject: BIOLOGIA MOLECULAR / BIOTECNOLOGIA Year: 1995 Document type: Article Affiliation country: France Country of publication: United kingdom

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