The Cys292-->Ala substitution in protein R1 of class I ribonucleotide reductase from Escherichia coli has a global effect on nucleotide binding at the specificity-determining allosteric site.

Ormö, M; Sjöberg, B M

Ormö, M; Sjöberg, B M.

Affiliation

Ormö M; Department of Molecular Biology, Stockholm University, Sweden.

Eur J Biochem ; 241(2): 363-7, 1996 Oct 15.

Article in En | MEDLINE | ID: mdl-8917431

Subject(s)

Escherichia coli/enzymology; Ribonucleotide Reductases/chemistry; Allosteric Site/genetics; Amino Acid Sequence; Escherichia coli/genetics; Models, Molecular; Molecular Structure; Nucleotides/metabolism; Point Mutation; Protein Conformation; Ribonucleotide Reductases/classification; Ribonucleotide Reductases/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Ribonucleotide Reductases / Escherichia coli Language: En Journal: Eur J Biochem Year: 1996 Document type: Article Affiliation country: Sweden Country of publication: United kingdom

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