Differential activation of endopeptidase EC 3.4.24.15 toward natural and synthetic substrates by metal ions.

Wolfson, A J; Shrimpton, C N; Lew, R A; Smith, A I

Wolfson, A J; Shrimpton, C N; Lew, R A; Smith, A I.

Affiliation

Wolfson AJ; Peptide Biology Laboratory, Baker Medical Research Institute, Prahran, Victoria, Australia.

Biochem Biophys Res Commun ; 229(1): 341-8, 1996 Dec 04.

Article in En | MEDLINE | ID: mdl-8954129

Subject(s)

Metalloendopeptidases/metabolism; Animals; Calcium/pharmacology; Cations, Divalent/pharmacology; Dose-Response Relationship, Drug; Enzyme Activation; Fluorescent Dyes/metabolism; Hydrolysis; Male; Manganese/pharmacology; Metalloendopeptidases/antagonists & inhibitors; Metalloendopeptidases/drug effects; Metalloendopeptidases/genetics; Oligopeptides/metabolism; Protease Inhibitors/pharmacology; Rats; Recombinant Proteins/antagonists & inhibitors; Recombinant Proteins/drug effects; Recombinant Proteins/metabolism; Substrate Specificity; Testis/enzymology; Zinc/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Metalloendopeptidases Limits: Animals Language: En Journal: Biochem Biophys Res Commun Year: 1996 Document type: Article Affiliation country: Australia Country of publication: United States

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