Thromboxane inhibition potentiates antihypertensive effects of alpha 1 adrenoceptor antagonists in the rat.

Takada, S; Numabe, A; Hirawa, N; Yagi, S; Uehara, Y

Takada, S; Numabe, A; Hirawa, N; Yagi, S; Uehara, Y.

Affiliation

Takada S; Department of Medicine, Dokkyo University School of Medicine, Mibu, Japan.

Prostaglandins Leukot Essent Fatty Acids ; 56(2): 127-34, 1997 Feb.

Article in En | MEDLINE | ID: mdl-9051722

Subject(s)

Adrenergic alpha-Antagonists/pharmacology; Antihypertensive Agents/pharmacology; Blood Pressure/drug effects; Thromboxanes/antagonists & inhibitors; Animals; Aorta; Body Weight/drug effects; Cells, Cultured; Drug Synergism; Eicosanoids/metabolism; Eicosanoids/urine; Ethanolamines/pharmacology; Kidney/drug effects; Kidney/metabolism; Methacrylates/pharmacology; Muscle, Smooth, Vascular/drug effects; Muscle, Smooth, Vascular/metabolism; Prazosin/pharmacology; Quinazolines/pharmacology; Rats; Rats, Inbred SHR; Sodium/metabolism; Sodium/urine; Thromboxane-A Synthase/antagonists & inhibitors; Thromboxanes/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Blood Pressure / Thromboxanes / Adrenergic alpha-Antagonists / Antihypertensive Agents Limits: Animals Language: En Journal: Prostaglandins Leukot Essent Fatty Acids Journal subject: ENDOCRINOLOGIA Year: 1997 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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