Downregulation of cyclin G1 expression by retrovirus-mediated antisense gene transfer inhibits vascular smooth muscle cell proliferation and neointima formation.

Zhu, N L; Wu, L; Liu, P X; Gordon, E M; Anderson, W F; Starnes, V A; Hall, F L

Zhu, N L; Wu, L; Liu, P X; Gordon, E M; Anderson, W F; Starnes, V A; Hall, F L.

Affiliation

Zhu NL; USC Gene Therapy Laboratories, Childrens Hospital of Los Angeles, and the University of Southern California School of Medicine, 90027, USA.

Circulation ; 96(2): 628-35, 1997 Jul 15.

Article in En | MEDLINE | ID: mdl-9244236

Subject(s)

Carotid Arteries/pathology; Carotid Stenosis/pathology; Cell Movement/genetics; Cyclins/genetics; Gene Transfer Techniques; Genetic Therapy; Oligonucleotides, Antisense/genetics; Animals; Carotid Arteries/metabolism; Carotid Stenosis/metabolism; Carotid Stenosis/therapy; Cell Division/genetics; Cells, Cultured; Cyclin G; Cyclin G1; Cyclins/biosynthesis; Down-Regulation; Genetic Vectors; Oligonucleotides, Antisense/administration & dosage; Rats; Rats, Wistar; Retroviridae; Tunica Intima/metabolism; Tunica Intima/pathology

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Collection: 01-internacional Database: MEDLINE Main subject: Genetic Therapy / Carotid Arteries / Cell Movement / Oligonucleotides, Antisense / Carotid Stenosis / Cyclins / Gene Transfer Techniques Type of study: Prognostic_studies Limits: Animals Language: En Journal: Circulation Year: 1997 Document type: Article Affiliation country: United States Country of publication: United States

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