Inhibition of NADPH oxidase-mediated superoxide radical formation in PMA-stimulated human neutrophils by 4-hydroxynonenal--binding to -SH and -NH2 groups.

Siems, W G; Capuozzo, E; Verginelli, D; Salerno, C; Crifò, C; Grune, T

Siems, W G; Capuozzo, E; Verginelli, D; Salerno, C; Crifò, C; Grune, T.

Affiliation

Siems WG; Herzog-Julius Hospital of Rheumatology and Orthopaedics, Bad Harzburg, Germany.

Free Radic Res ; 27(4): 353-8, 1997 Oct.

Article in En | MEDLINE | ID: mdl-9416463

Subject(s)

Aldehydes/pharmacology; Carcinogens/pharmacology; Cysteine Proteinase Inhibitors/pharmacology; NADPH Oxidases/metabolism; Neutrophils/metabolism; Tetradecanoylphorbol Acetate/pharmacology; Free Radicals/metabolism; Humans; NADPH Oxidases/antagonists & inhibitors; Neutrophil Activation/drug effects; Superoxides/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Tetradecanoylphorbol Acetate / Carcinogens / Cysteine Proteinase Inhibitors / NADPH Oxidases / Aldehydes / Neutrophils Limits: Humans Language: En Journal: Free Radic Res Journal subject: BIOQUIMICA Year: 1997 Document type: Article Affiliation country: Germany Country of publication: United kingdom

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