Corticotropin-releasing factor inhibits luteinizing hormone-stimulated P450c17 gene expression and androgen production by isolated thecal cells of human ovarian follicles.

Erden, H F; Zwain, I H; Asakura, H; Yen, S S

Erden, H F; Zwain, I H; Asakura, H; Yen, S S.

Affiliation

Erden HF; Department of Reproductive Medicine, University of California-San Diego, La Jolla 92093-0633, USA.

J Clin Endocrinol Metab ; 83(2): 448-52, 1998 Feb.

Article in En | MEDLINE | ID: mdl-9467556

Subject(s)

Androgens/biosynthesis; Corticotropin-Releasing Hormone/pharmacology; Gene Expression/drug effects; Luteinizing Hormone/pharmacology; Steroid 17-alpha-Hydroxylase/genetics; Theca Cells/enzymology; Adult; Androstenedione/biosynthesis; Blotting, Northern; Culture Media; Dehydroepiandrosterone/biosynthesis; Female; Humans; Kinetics; RNA, Messenger/metabolism; Steroid 17-alpha-Hydroxylase/metabolism; Theca Cells/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Theca Cells / Corticotropin-Releasing Hormone / Luteinizing Hormone / Steroid 17-alpha-Hydroxylase / Gene Expression / Androgens Limits: Adult / Female / Humans Language: En Journal: J Clin Endocrinol Metab Year: 1998 Document type: Article Affiliation country: United States Country of publication: United States

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