Aerosol-induced immunoglobulin (Ig)-E unresponsiveness to ovalbumin does not require CD8+ or T cell receptor (TCR)-gamma/delta+ T cells or interferon (IFN)-gamma in a murine model of allergen sensitization.

Seymour, B W; Gershwin, L J; Coffman, R L

Seymour, B W; Gershwin, L J; Coffman, R L.

Affiliation

Seymour BW; Department of Immunobiology, DNAX Research Institute of Molecular and Cellular Biology, Palo Alto, California 94304, USA.

J Exp Med ; 187(5): 721-31, 1998 Mar 02.

Article in En | MEDLINE | ID: mdl-9480982

Subject(s)

Allergens/administration & dosage; CD8-Positive T-Lymphocytes/immunology; Immunoglobulin E/immunology; Interferon-gamma/physiology; Receptors, Antigen, T-Cell, gamma-delta/immunology; T-Lymphocyte Subsets/immunology; Aerosols; Animals; Cytokines/metabolism; Desensitization, Immunologic; Eosinophils/immunology; Immunoglobulin G/immunology; Lung/immunology; Lymphocyte Depletion; Mice; Mice, Inbred BALB C; Mice, Knockout; Ovalbumin/administration & dosage; Th2 Cells/immunology; beta 2-Microglobulin/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin E / Allergens / T-Lymphocyte Subsets / Interferon-gamma / Receptors, Antigen, T-Cell, gamma-delta / CD8-Positive T-Lymphocytes Limits: Animals Language: En Journal: J Exp Med Year: 1998 Document type: Article Affiliation country: United States

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