The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

Stott, F J; Bates, S; James, M C; McConnell, B B; Starborg, M; Brookes, S; Palmero, I; Ryan, K; Hara, E; Vousden, K H; Peters, G

Stott, F J; Bates, S; James, M C; McConnell, B B; Starborg, M; Brookes, S; Palmero, I; Ryan, K; Hara, E; Vousden, K H; Peters, G.

Affiliation

Stott FJ; Imperial Cancer Research Fund Laboratories, P.O. Box 123, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

EMBO J ; 17(17): 5001-14, 1998 Sep 01.

Article in En | MEDLINE | ID: mdl-9724636

Subject(s)

Alternative Splicing; Cyclin-Dependent Kinase Inhibitor p16/metabolism; Gene Expression Regulation, Neoplastic; Nuclear Proteins; Proteins/metabolism; Proto-Oncogene Proteins/metabolism; Tumor Suppressor Protein p53/metabolism; Amino Acid Sequence; Cell Cycle/physiology; Cyclin-Dependent Kinase Inhibitor p16/genetics; Feedback; Humans; Models, Genetic; Molecular Sequence Data; Protein Binding; Proteins/genetics; Proto-Oncogene Proteins c-mdm2; Sequence Homology, Amino Acid; Tumor Suppressor Protein p14ARF

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / Proteins / Gene Expression Regulation, Neoplastic / Tumor Suppressor Protein p53 / Proto-Oncogene Proteins / Alternative Splicing / Cyclin-Dependent Kinase Inhibitor p16 Limits: Humans Language: En Journal: EMBO J Year: 1998 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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