Activation of a Ca2+-dependent K+ current in mouse fibroblasts by lysophosphatidic acid requires a pertussis toxin-sensitive G protein and Ras.

Repp, H; Koschinski, A; Decker, K; Dreyer, F

Repp, H; Koschinski, A; Decker, K; Dreyer, F.

Affiliation

Repp H; Rudolf-Buchheim-Institut für Pharmakologie, Justus-Liebig-Universität Giessen, Germany.

Naunyn Schmiedebergs Arch Pharmacol ; 358(5): 509-17, 1998 Nov.

Article in En | MEDLINE | ID: mdl-9840418

Subject(s)

Calcium/physiology; GTP-Binding Proteins/drug effects; Lysophospholipids/pharmacology; Pertussis Toxin; Potassium Channels/drug effects; Virulence Factors, Bordetella/pharmacology; ras Proteins/drug effects; 3T3 Cells/cytology; 3T3 Cells/drug effects; 3T3 Cells/physiology; Animals; GTP-Binding Proteins/metabolism; Membrane Potentials/drug effects; Mice; Patch-Clamp Techniques; Potassium Channels/physiology; Reproducibility of Results; Signal Transduction/drug effects; Signal Transduction/physiology; ras Proteins/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Virulence Factors, Bordetella / Lysophospholipids / Potassium Channels / Calcium / Ras Proteins / GTP-Binding Proteins / Pertussis Toxin Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Naunyn Schmiedebergs Arch Pharmacol Year: 1998 Document type: Article Affiliation country: Germany Country of publication: Germany

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