Processing of switch transcripts is required for targeting of antibody class switch recombination.

Hein, K; Lorenz, M G; Siebenkotten, G; Petry, K; Christine, R; Radbruch, A

Hein, K; Lorenz, M G; Siebenkotten, G; Petry, K; Christine, R; Radbruch, A.

Affiliation

Hein K; Deutsches Rheuma-Forschungszentrum Berlin, 10115 Berlin, Germany.

J Exp Med ; 188(12): 2369-74, 1998 Dec 21.

Article in En | MEDLINE | ID: mdl-9858523

Subject(s)

Immunoglobulin Class Switching; Immunoglobulin G/genetics; Immunoglobulin Switch Region/genetics; RNA Splicing/genetics; Recombination, Genetic; Adenoviridae/genetics; Animals; B-Lymphocytes/drug effects; B-Lymphocytes/immunology; B-Lymphocytes/metabolism; Exons/genetics; Female; Genetic Vectors; Genotype; Immunoglobulin G/metabolism; Immunoglobulin Switch Region/immunology; Interleukin-4/immunology; Interleukin-4/pharmacology; Lipopolysaccharides/pharmacology; Lymphocyte Activation/drug effects; Male; Mice; Mice, Inbred Strains; Mice, Transgenic; Mutagenesis, Site-Directed; Promoter Regions, Genetic/genetics; RNA Splicing/drug effects; Recombination, Genetic/drug effects; Regulatory Sequences, Nucleic Acid/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombination, Genetic / Immunoglobulin G / Immunoglobulin Switch Region / RNA Splicing / Immunoglobulin Class Switching Limits: Animals Language: En Journal: J Exp Med Year: 1998 Document type: Article Affiliation country: Germany Country of publication: United States

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