Oral administration of (-)catechin protects against ischemia-reperfusion-induced neuronal death in the gerbil.

Inanami, O; Watanabe, Y; Syuto, B; Nakano, M; Tsuji, M; Kuwabara, M

Inanami, O; Watanabe, Y; Syuto, B; Nakano, M; Tsuji, M; Kuwabara, M.

Affiliation

Inanami O; Department of Radiation Biology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan. inanami@vetmed.hokudai.ac.jp

Free Radic Res ; 29(4): 359-65, 1998 Oct.

Article in En | MEDLINE | ID: mdl-9860051

Subject(s)

Catechin/pharmacology; Hippocampus/pathology; Ischemic Attack, Transient/pathology; Neurons/drug effects; Reperfusion Injury/drug therapy; Administration, Oral; Animals; Antioxidants/administration & dosage; Antioxidants/pharmacology; Blood-Brain Barrier; Catechin/administration & dosage; Cell Death/drug effects; Cyclic N-Oxides/metabolism; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Free Radical Scavengers/metabolism; Gerbillinae; Hippocampus/drug effects; Hippocampus/metabolism; Ischemic Attack, Transient/drug therapy; Ischemic Attack, Transient/metabolism; Neurons/pathology; Prosencephalon/drug effects; Prosencephalon/metabolism; Prosencephalon/pathology; Reactive Oxygen Species/metabolism; Reperfusion Injury/metabolism; Reperfusion Injury/pathology; Spin Labels; Superoxides/metabolism; Xanthine Oxidase/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Reperfusion Injury / Catechin / Ischemic Attack, Transient / Hippocampus / Neurons Limits: Animals Language: En Journal: Free Radic Res Journal subject: BIOQUIMICA Year: 1998 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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