Phenotypic consequences of a nonsense mutation in the leptin receptor gene (fak) in obese spontaneously hypertensive Koletsky rats (SHROB).

Ishizuka, T; Ernsberger, P; Liu, S; Bedol, D; Lehman, T M; Koletsky, R J; Friedman, J E

Ishizuka, T; Ernsberger, P; Liu, S; Bedol, D; Lehman, T M; Koletsky, R J; Friedman, J E.

Affiliation

Ishizuka T; Departments of Nutrition, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.

J Nutr ; 128(12): 2299-306, 1998 Dec.

Article in En | MEDLINE | ID: mdl-9868173

Subject(s)

Carrier Proteins/genetics; Obesity/genetics; Point Mutation; Proteins/metabolism; Receptors, Cell Surface; Animals; Female; Glucose/metabolism; Humans; Leptin; Male; Muscle, Skeletal/drug effects; Muscle, Skeletal/metabolism; Obesity/metabolism; Phenotype; Proteins/genetics; Proteins/pharmacology; RNA, Messenger/genetics; Rats; Rats, Inbred SHR; Rats, Mutant Strains; Receptors, Leptin; Signal Transduction/physiology; Species Specificity

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Collection: 01-internacional Database: MEDLINE Main subject: Proteins / Carrier Proteins / Point Mutation / Receptors, Cell Surface / Obesity Limits: Animals / Female / Humans / Male Language: En Journal: J Nutr Year: 1998 Document type: Article Affiliation country: United States Country of publication: United States

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