A preliminary study of neopterin as a potential marker for severe dengue virus infection
Transactions of the Royal Society of Tropical Medicine and Hygiene
; 93(4): 447-448, July/August 1999. tab
Article
in English
| MedCarib
| ID: med-17311
Responsible library:
TT5
Localization: TT5; W1 TR227M
ABSTRACT
Dengue virus cause the non-fatal dengue fever and the life-threating dengue haemorrhagic fever/dengue shock syndrome (DHF/DSS). Early clinical features of DF and DHF/DSS are indistinguishable and it is difficult to identify early DHF/DSS using clinical and laboratory parameters. A prospective observational study (KALAYANAROOJ et al, 1997) of Thai children with fever for less than 72h revealed that, at enrolment, plasma aspartate aminotransferase (AST)levels were significantly raised in children who developed DHF but were of relatively low positive predictive value (PPV=0.27 for AST>40U/mL). MONATH (1997), in his review of the paper by Kalayanaroo et al., noted the lack of 'clear clinical prognostic indicators for DHF' and called for strategies to improve diagnosis (AU)
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Collection:
International databases
Health context:
Neglected Diseases
Health problem:
Dengue
/
Neglected Diseases
Database:
MedCarib
Main subject:
Homeopathic Clinical-Dynamic Prognosis
/
Severe Dengue
/
Neopterin
/
Dengue
/
Dengue Virus
Type of study:
Observational study
Limits:
Humans
Language:
English
Journal:
Transactions of the Royal Society of Tropical Medicine and Hygiene
Year:
1999
Document type:
Article
Institution/Affiliation country:
The University of the West Indies/Trinidad and Tobago