Prolonged childhood Cushing syndrome secondary to intralesional triamcinolone acetonide
Annals of tropical paediatrics
; 22(1): 89-91, Mar. 2002.
Article
in English
| MedCarib
| ID: med-17604
Responsible library:
TT5
Localization: TT5; W1, AN627U
ABSTRACT
Intralesional corticosteroids have been used in the treatment of hypertrophic keloid scars for over 40 years. The few complications documented have mostly been local skin changes, viz depigmentation and cutaneous atrophy. Cushing's syndrome following intralesional injection is rare and usually self-limiting following cessation of therapy. This report describes a 9-year-old girl who developed Cushing's syndrome 2-3 weeks after a single treatment with 40 mg triamcinolone acetonide injected into keloids. Features of Cushing's syndrome and a suppressed hypothalamic-pituitary axis were present up to 9 months later. Three years after glucocorticoid injections, features of Cushing's syndrome had largely disappeared. Dosages of intralesional steroids normally recommended for adults are inappropriate for children.
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Collection:
International databases
Database:
MedCarib
Main subject:
Trinidad and Tobago
/
Triamcinolone Acetonide
/
Injections, Intralesional
/
Cushing Syndrome
Limits:
Adult
/
Child
/
Humans
Country/Region as subject:
English Caribbean
/
Trinidad and Tobago
Language:
English
Journal:
Annals of tropical paediatrics
Year:
2002
Document type:
Article
Institution/Affiliation country:
The University of the West Indies/Trinidad and Tobago